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Morse - O - Tool

Pharmaceutical Dwell Time Calculator

Professional tablet manufacturing dwell time calculator with quality assessment

Calculate precise dwell times for tablet compression with automatic quality assessment, temperature corrections, and regulatory compliance features for pharmaceutical manufacturing.

Process Parameters

Range: 4-20 mm. Compression surface diameter of the punch.
Range: 200-600 mm. Distance between punch centers on turret.
Range: 10-100 RPM. Rotational speed of the tablet press turret.
Optional: 5-50 kN. For pressure calculations.
Manufacturing temperature. Affects material properties.
Type of tablet compression equipment.
Standard tooling sizes for tablet presses.
Manufacturing process affects dwell time requirements.

Dwell Time Quality Guidelines

Range (ms)AssessmentImpact
< 5 msCritical LowCompression defects likely
5 - 8 msBelow OptimalMonitor tablet hardness
8 - 35 msOptimal RangeGood compression conditions
35 - 50 msAbove OptimalRisk of over-compression
> 50 msCritical HighOver-compression likely

Results are based on pharmaceutical manufacturing standards. Always validate with your equipment specifications and internal SOPs.

Disclaimer: Results are approximate, we assume no liability for their accuracy

Frequently Asked Questions

How is dwell time calculated?

Dwell Time = (Head Flat Diameter × 1000) ÷ (Turret Speed × π × Pitch Circle Diameter ÷ 60). The result is adjusted for temperature and formulation type.

What affects dwell time quality?

Optimal dwell time (8-35ms) ensures proper tablet formation. Too short causes weak tablets, too long can cause over-compression and tool wear.

How does temperature affect calculations?

Higher temperatures soften materials, requiring correction factors. Each degree above 25°C increases dwell time by 1.5%.

What are the formulation adjustments?

Wet granulation: 95% of base time, Dry granulation: 105%, Direct compression: 110%, High-dose API: 115% due to compression characteristics.